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Although protein synthesis is required for chronic tolerance, it is not required for the development of rapid tolerance and is unlikely to occur during the brief timescale of acute ethanol intoxication (~30 min; Berger et al. 2004).
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However, our results indicate that increasing Hsp70 gene expression levels are associated with increases in the expression of other Hsp genes, at least over brief timescales.
In particular, as also reported by Webster and Miyahara (1997), the threshold changes were virtually identical whether observers were adapted to a spectral slope of − 1 or − 1.5 and it was only for larger deviations that substantially different CSFs may emerge, at least for the brief timescales assessed in our study.
Bistability, and permanent synaptic strengthening by tetani, were seen when ongoing activity consisted of brief periods of Ca2+ elevation separated by intervals (timescale of minutes) without activity.
Bistability, and permanent synaptic strengthening by tetani, were seen when the ongoing activity consisted of brief periods of Ca2+ elevations, at theta-rhythm frequency, with the periods separated by intervals (timescale of minutes) without activity.
We were surprised by the timescale of weeks," added Jones.
Do we have a good idea of the timescale of this response?
By Elizabeth Kolbert On the timescale of evolutionary history, paleo enthusiasts note, agriculture is a fad.
But no-one can tell the timescale of catastrophic releases.
For aircraft, the timescale of the challenge is similar.
The timescale of erosion of limestone is thousands of years, according to Anthony Cooper of the BGS.
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