According to the IOM report, the vaccine can create swelling and nodules at the injection site, fever and malaise, and in some people a period of "brief functional impairment".
The biopsy caused some brief voice impairment, and indicated that Kimball had a throat infection but not cancer.
The Brief Disability Questionnaire (BDQ) [ 42] was used to assess social and occupational role impairment based on an 11-item self-rated tool.
We propose that a disturbed lactate shuttle in ADHD accounts for brief transient impairments in rapid neuronal firing and delayed myelination: Together they result in variable responses.
Other patient characteristics were derived from a variety of sources: Nurses administered the VES-13, and assessments of functional status (Katz Assessment for Functional Status) [ 21], cognitive impairment (Brief Interview for Mental Status) [ 22] and symptoms of depression (Patient Health Questionnaire-2) [ 23].
Main Outcome Measures: Shoulder subluxation (radiograph), shoulder pain (Brief Pain Inventory), motor impairment (Fugl-Meyer score), shoulder pain-free external rotation (handheld goniometer), and disability (FIM™ instrument) were assessed before treatment (T1), after 6 weeks of neuromuscular stimulation (T2), and at 3-month follow-up (T3).
Because of its simplicity, brevity, and high face validity, and because of the lack of competing brief measures of functional impairment, the SDS has become a widely used outcome measure in clinical trials of a variety of mental health disorders.
Owing to limited knowledge of the course of juvenile MLD, its rapid progression, and new potential treatments in development, a brief measure of observable impairments associated with this disorder that are meaningful to patients/parents is needed.
50 51 To our knowledge, there is no published evidence to suggest that skin temperature elevations would result in such impairments during brief explosive efforts (ie, 15 m sprints and jumps), especially when given the opportunity to recover between bouts.
