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In brief, gene predictions were done using a combination of GeneMark and Glimmer [80], [81], [82].
In brief, gene expression profiles were established from 80 frozen glioblastoma (grade IV astrocytoma), comprising 70 tumors from initial surgery, and 10 samples resected at recurrence, and from four non-neoplastic brain tissue samples.
In brief, gene presence or gene absence was treated as a binary character (0,1) state.
In brief, gene families were aligned in ClustalW version 1.83 (Thompson et al. 1994).
In brief, gene expression profiles can be determined from samples of a variety of tissue types, including brain and blood.
A detailed list of investigated genes is reported in Table 1, along with brief gene function descriptions.
Similar(49)
In brief, gene-specific biotin-labelled cDNA probes were generated from 2.5 μg total RNA using gene-specific primers for reverse transcription using 200 U MMLV reverse transcriptase (Promega, Southampton, UK) and 40 U RNase inhibitor (Promega).
In brief, genes overexpressed in the well-differentiated tumours are upregulated in primitive and genes underexpressed in the well-differentiated tumours are downregulated in primitive subtype.
In brief, genes, polymorphisms, outcomes investigated, patient characteristics, results of the statistical tests for outcome measure(s) investigated, and other relevant information are curated from eligible published reports and are posted in the dbCPCO database.
In brief, if gene A shows enough sequence similarity to gene B, and gene B shows enough sequence similarity to gene C, even if gene A is not similar to gene C, genes A, B and C will be put into one cluster.
In brief, many gene families from transcription factors to effector genes involved in detoxification, binding, and transport of xenobiotics were characterized in this study.
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