Newburg, Long and Breslow [99, 100] suggested that the active agent was a highly polarised bimetallic species (15) containing Ti and Al bridged by chlorine (Scheme 1).
This compound, which consists of tin, bridging oxygen, and chlorine ligands, may form ladder-like clustered structures and coordinate to atoms with lone electron pairs, such as the nitrogen in pyridine (Dehnicke, 1961; Messin and Janierdubry, 1979; Holmes et al., 1987; Sakurada et al., 2000), or as is perhaps more functionally relevant, the imidazole groups of histidine residues in proteins.
There, the chlorine bridges can be replaced, for instance, by iodine, hydrogen or nitrogen atoms or by CN groups.
In these cases, such bending was imposed by the use of rigid bidentate ligands, 36– 39 which in one case is also supported by a chlorine atom bridging two different metal centers (Pd Cl Pt).
Remove remaining chlorine from the chlorinator.
The analysis of the structural properties of the MnL2(H2O)2(Clead2 lead to the design of dinuclear complex {(μ-Cl MnL2(PF6)} where two chlorine atoms were utilized as bridging moieties.
Molecular models showed that the dihedral angle between these protons is close to 90° when the chlorine is syn to the one carbon bridge, as in 83.
Nucleophilic substitutions of the reactive chlorine atoms in either cyanuric or phosphonitrilic chloride by the bridging 1,4-phenylenediamine and benzidine units lead to the formation of two- (2-D) or three-dimensional (3-D) covalent networks, according to the spatial arrangement of the chlorine atoms in each particular triazine core.
The opportunity to cross the bridge and expose my four sons to a day of culture rather than a day of chlorine: priceless.
