Sentence examples for bridging channels from inspiring English sources
Immunofluorescent microscopy of frozen splenic sections also revealed HEL-positive cells within the marginal zone, red-pulp, bridging channels, and T cell zone of NZB, but not B6 dTg mice.
EBI2-mediated positioning in bridging channels promotes DC encounter with blood-borne particulate antigen.
The factors that promote CD4+ DC positioning in MZ bridging channels have been unclear.
Under homeostatic conditions, EBI2 has a dominant influence and promotes positioning in MZ bridging channels.
3: Upon outmigration through bridging channels, CXCR3Hi CD62LLo CD8+ T cells continue to proliferate in clusters found in the MZ.
Refer to Figure 8 figure supplement 1 for IHC image of EdU+ CD8+ T cells in splenic bridging channels.
An oblique bridging channel forms between the left and right anterior cardinal veins, which shifts systemic venous return to the right SVC and into the right atrium.
Enlarge inset depicts proliferating and non-proliferating double stained CD8+ T cells in the bridging channel.
MZ bridging channel positioning facilitates DC capture of blood-borne particulate antigen and rapid movement to T zone.
10.7554/eLife.00757.014 Figure 8. Model for the role of EBI2 in mediating marginal zone (MZ) bridging channel positioning of CD4+ DCs in the spleen.
Following particulate antigen exposure, DCs migrate in a CCR7-dependent manner from the bridging channel in to the T zone where they present antigen to helper T cells.
