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Furthermore, there was significantly more trabecular bridging after six weeks in the LIPUS group (81,2%) compared to the placebo group (54,6%) [ 13].
Significant increases in LOS remained for UFH and two-agent bridging after adjustment for demographic and clinical variables including diabetes and cancer.
In contrast, the use of thiophenol as an improved leaving group led to complete bridging after 10 min with just 1 equiv of reagent 5, at a rate comparable to that of dibromomaleimide 1.
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