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It is the rare researcher who can bridge discoveries into human trials for further development.
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A key component of bridging discovery-based research to the clinic is communication of results, and CDDis is uniquely positioned to contribute to this goal.
The work is a series of ornate tableaus that successively portray the arrival of the first steamboat, the construction of the Brooklyn Bridge, the discovery of the electric battery by Alessandro Volta, the invention of the telegraph, the opening of the Suez Canal, the first attempt to build a canal across Panama and the tunneling under Mount Cenis that linked Italy and France in 1871.
29 In September 2003, the article reported that someone who had contemplated suicide at Bloor Street Viaduct subsequently jumped from a nearby bridge on discovery of the barrier.
Translational research that bridges scientific discoveries to clinical application involves the use of animal models in order to assess safety and efficacy for regulatory approval for human use.
Furthermore, we describe how developability can in fact emerge as a "bridge" between discovery and development functions, raising CQAs awareness very early on as well as aligning the objectives of different stakeholders towards developing better, safer, and more cost-effective products.
But here's an example: The National Institutes of Health Office of Technology Transfer (NIH OTT) is the bridge between the discoveries of intramural investigators within the NIH, the Food and Drug Administration FDAand and the Centers for Disease Control and Prevention CDCC) and products based on those discoveries.
This is more than an extension of NIH's role in promoting research into rare diseases; it's potentially a model for the role NIH could play more broadly in helping promising basic discoveries bridge the "valley of death" between preclinical development and clinical research.
The idea is to create a bridge from serendipitous discovery of a single video to a sustained viewing session.
Given the paucity of literature on how to sustain health research networks and how to progress knowledge translation across disciplines in health networks, it is important to engage with clinicians to bridge gaps between discovery and implementation [ 17] and to identify methods and measures for evaluating 'team science' [ 18].
But medical research philanthropy, funded largely by patients themselves, is uniquely motivated to bridge the gap between discoveries in university labs, drug development efforts within companies, and therapies in the clinic.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com