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For example, in breeding index calculations, the effect of SNP genotype miscalls that occur with a low frequency, will be small and thus will not influence the overall result of the breeding value of an individual cattle.
Because humans have lost the ability to synthesize AsA, its content is an important breeding index for crop plants.
Breeding index or Best Linear Unbiased Prediction (BLUP) [ 15, 16] was used for comparison of performance potential with the total population of cold-blooded trotters and between horses examined with different grades of OUC.
Breeding index and official sports data originating from strict protocols kept by groups of officials in trotting associations was used for comparison of performance of these horses that together had competed in more than 23,000 races between 1973 and 2009.
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The inclusion of immune response traits in breeding indices has been suggested to improve inherent disease resistance in dairy cattle [ 1, 2].
This study found a number of significant SNP markers associated with High and Low general antibody and cell-mediated immune responses of Holstein cattle, suggesting it may be possible to calculate genomic breeding values for these traits and include them in breeding indices to decrease the incidence and severity of disease in the dairy industry.
The advent of genomic selection has significantly increased the rate of genetic gain in dairy cattle mainly by reducing the generation interval [ 60], and could make it feasible to include new phenotypes such as methane production or health in breeding indices [ 61].
However, the inclusion of new traits in genomic breeding indices will require a substantial reference population with accurate phenotypes and genotypes.
The significant genetic variation associated with AMIR and CMIR in this study may imply feasibility to include immune response in genomic breeding indices as an approach to improve inherent animal health.
At the studbook evaluation, a trotter-type horse must meet the standards in racing results and/or in breeding value index as decreed by Suomen Hippos.
To some extent, consideration was also taken to the bull-breeding index for calving ease, in which a bull with a low incidence of calving difficulty (a high index for calving ease) was preferred.
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