This could be caused by confounding variables that may be associated with SALP, including breed variability, underlying disease processes and differences in detection methods.
Given that significant differences in covariate ranges were intrinsically associated to each breed, each variable was adjusted and compared with the mean covariate value of each breed [ 71].
However, among 14 breeds with variable or intermediate ear types, the strongest signal was seen in the CFA10 region, with the highest significance near a SNP identified previously using all breeds (CFA10 11,169,556; pgenome-wide = 0.097; Additional file 2: Figure S1, Additional file 1: Table S1).
The variable breed was dichotomized into pedigree and non-pedigree cats for statistical analysis because the number of cats per breed was small.
The treatment protocol used and the variables recorded at the date of first diagnosis, with the exception of the variable breed, were evaluated in a univariate Cox proportional hazard model and used to generate hazard ratios (HRs).
The final model contained the variables, breed category and herd size.
Therefore, further studies are indicated to assess intervertebral disk width in different dog breeds with a variable body conformation.
The procedure for repeated measurements using PROC MIXED was employed for evaluating effects of variables (breed, time, parity and time × parity) on the hormonal levels.
While their study did not make any definite recommendation, it provided a wide perspective on how genetic variation is distributed among peripheral and more variable breeds, which can be helpful for decision-makers to carry out conservation programs.
These breeds are highly variable, located on basal short branches in the neighbor-joining tree, close to the origin of the principal component analysis plot and, although highly admixed, they are quite distinct from those reared on the western side of the Zagros mountain range.
