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These results indicate a potential for automated detection based on breath sampling.
Solid-phase microextraction was also valuable for detection of residual VOCs in the breath sampling device that resulted in optimisation of cleaning procedures.
Such a design can help quantify the influence of and optimize breath sampling parameters that will reduce total measurement variability and enhance overall forensic confidence.
This new method provides abundant data compared to previous discrete time-integrated breath sampling methods.
However, it is also related with the breath sampling length and frequency.
All patients and volunteers consumed food not later than one hour before breath sampling.
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Or the healthy breath samples could have been collected in a different room on different days.
Breath samples were collected at baseline and every 15 min postprandially until 4 h.
Breath samples obtained from 10 volunteers and spiked samples were investigated.
Practical application of this device is demonstrated by measuring NO in human breath samples.
Some individuals with lung diseases have difficulty in providing evidential breath samples using the device.
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