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Moreover, room air concentrations of these aldehydes were generally much higher than in breath (data not shown), suggesting an additional influx of these analytes from the surrounding atmosphere.
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Among ILI patients, there were no significant differences in the presence of cough, sore throat, rhinorrhea, sputum production, pleuritic chest pain, difficult breathing or shortness of breath by age (data not shown).
The mean breathing rate of the sham group animals was approximately 50 breaths per minute (data not shown).
In the total population homozygothy of the rs2486064 A allele was positively associated with shortness of breath when at rest (OR 1.33 (95% CI, 1.06; 1.68), p = 0.05) whereas homozygosity of the minor A allele of rs2886117 were protective against shortness of breath when at rest (OR 0.43 (95% CI, 0.18; 0.98), p = 0.02)(data not shown).
The dose level of 100 μg RM-131 was chosen based on the safety, tolerability, PK profile, and PD profile (GE breath test) established in a phase 1 single-ascending dose study of healthy normal volunteers (data not shown).
In all animals of the shock groups, the respiratory rate was approximately 60 breaths per minute during shock induction, the shock period and the post-resuscitation phase (data not shown).
(Data not shown).
p.i (data not shown).
(detailed data not shown).
SLS showed similar results (data not shown).
However, dystrophin was not (data not shown).
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