Sentence examples for breast tumours and to from inspiring English sources
BRCA1 methylation has been shown to occur in sporadic breast tumours and to be associated with reduced gene expression.
Molecular profiling using a large panel of genes could help to classify breast tumours and to define signatures which are predictive of their clinical behaviour.
Maspin expression has been found to decrease with increasing malignancy in primary breast tumours, and to be absent from distant metastases (Zou et al, 1994).
The purposes of this study were to analyse the genotype of TGF-β1 at T29C and TGF- β1 phenotype in breast tumours, and to evaluate their associations with IGFs and clinical characteristics of breast cancer.
The present study is the first to describe in situ expression of IL-17 protein in human breast tumours and to propose a direct association between IL-17 and breast cancer invasion.
These features also make TNBC an ideal breast cancer sub-type to study how VEGF/NRP2 signalling functions in tandem with α6β1 to promote the initiation of breast tumours and to define the mechanism involved.
These data suggest that altered relative expression of these coregulators is unlikely to be a marker of tamoxifen sensitivity in OR+, node negative, primary breast tumours, and unlikely to have a functional role in de novo tamoxifen resistance.
CXCL12 promoter hypermethylation has been detected in primary breast tumours and contributes to their metastatic potential.
Its family member, CITED4, has been analysed in breast tumours and was found to be associated with HIF1 α expression and to be either lost or translocated into the cytoplasm during tumour progression (Fox et al, 2004).
We have also applied this method to successfully purify tumour parenchyma in CRC liver metastases, primary breast tumours, and with modification, to sort breast cancer bone marrow micrometastases.
Holland et al. based their observations initially on 171 breast tumours and then expanded to a total of 1001 primary breast carcinomas (Holland et al, 2011).
