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The alterations found in breast samples were observed in ovarian samples, whereas some additional alterations were observed in the ovarian samples as visually depicted in Figure 2.
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A positive correlation of differential expression between normal and malignant breast samples was observed for most SAS pairs.
The samples were observed by fluorescence microscopy.
Samples were observed with Axioskop (Zeiss).
Furthermore, using immunohistochemistry, enhanced staining of HER2 positive breast cancer tissue samples was observed with alkaline phosphatase fused scFvs compared to the monomeric counterpart.
The most obvious differences in the immunoreactive distribution between normal breast, primary and metastatic cancer tissue samples was observed in proteins located in the extracellular space surrounding normal breast ducts and primary and metastatic tumours.
In addition, 24 normal breast samples were used for comparison.
Chicken breast samples were purchased from a local retail store.
While no expression was detected in non-tumour samples, chimeric transcripts were observed in carcinoma (breast, lymph node, lung, ovary and pancreas) and sarcoma (skeletal muscle) samples.
In breast cancer samples only germline alterations were observed.
Overexpression of EZH2 has been detected in invasive breast carcinoma tissue samples and is observed in human breast tissue samples of morphologically normal lobules up to 12 years before the development of breast cancer.
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