By measuring the concentrations of the breast components, discrimination of benign and malignant tumours may be possible with diffuse optical imaging (Fig. 2A and B).
The smallest source of variation is the between-breast component, implying that normal material from a contralateral breast is a good surrogate for normal material from the affected breast.
This finding is consistent with the study done in rural Senegal that omitting breast feeding component from the index increase value to 0.82 [ 24].
The breast lobular component expands and differentiates with pregnancy and lactation transforming the relatively rudimentary gland into an alveolar rich lactation-competent structure [ 44].
Probably due to the use of complete hormone replacement therapy the lobular breast cancer component has continuously increased over the past decade from 9.5% in 1987 to 15.6% in 1999 [ 3].
Caries prevalence and severity levels were significantly lower in toddlers who were exclusively breastfed and those who received mixed feeding with a moderate high breast milk component, compared with toddlers who received low mixed feeding and those exclusively fed with formula (p < 0.01).
We observed a significantly higher relative expression of ERD5 messenger RNA in breast tumor components compared with matched adjacent normal breast tissue.
A higher relative expression of ERD3 messenger RNA in the normal breast tissue components compared with adjacent neoplastic tissue was found in the ER-positive subgroup.
The investigative approach was designed to detect and quantify the three molecules in specific breast tissue components, data that were not previously available.
This novel observation might link good response to tamoxifen to reformation of normal breast tissue components, such as cell-cell junctions (Lanigan et al., 2009).
These and other advantages have been linked to breast milk components, including fatty acids [ 1], growth factors [ 2], immunological factors [ 3, 4], live maternal cells [ 5, 6] and some genetic materials [ 7, 8].
