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Significant experience with this biopsy system exists in breast applications where efficacy and safety have been fully documented (12, 13).
Other groups have also reported more cases of in vivo fluorescence-DOT for human breast applications [ 28, 29].
It showed score 5 at the RTE, indicating no strain in the entire lesion and in the surrounding area: this aspect is considered related to malignant tissue with perinodular infiltration in the breast applications, thus to avoid a misdiagnosis we chose to classify it as malignant.
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VA technology may lead to a new clinical tool for breast imaging applications.
Because we are interested in developing this therapy for triple-negative breast cancer applications, we also explored the possibility of using an orthotopic tumor model established in the mammary gland fat pad.
The average duration of the breast compression application for MLO views reached its higher value in the middle of the work shift at 12 s.
The Results and discussion section describes the breast cancer application, implements the method on this data set, and discusses the assumptions of the models.
We believe that the GGM approach, which allows for continuous measurements, is more suitable for our breast cancer application, because the sample size is small.
Inverting for multiple chromophores such as hemoglobin, lipids and water has been shown to provide an improved ability to localize tumours or other objects of interest in the breast cancer application [ 6– 8].
These practices include bathing the baby immediately after birth, giving pre-lacteal feeds, delayed initiation of breast feeding, application of harmful substances on the cord and failure to keep babies warm [ 5, 6].
In breast cancer, application of single-cell sequencing approaches revealed a clonal sub-structure of primary tumors and the initiation of liver metastases as the result of expansion of individual primary clones [ 18, 20].
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