For example, ovarian cancer analyses controlled for parity, tubal ligation, and hysterectomy, whereas breast cancer analyses controlled for parity, age at first birth, hormone therapy use, duration of hormone therapy, and history of benign breast disease.
For the incident breast cancer analyses, breast cancer cases prevalent at baseline will be excluded.
Breast cancer analyses will also include previous benign breast disease (fibrocystic disease, intraductal papilloma or fibroadenoma).
For breast cancer analyses, person-time was accrued from the age at study enrolment.
The Vertical Transmission Study and breast milk analyses were approved by the Biomedical Research Ethics Committee of the University of KwaZulu-Natal.
Breast cancer analyses were additionally adjusted for mammography in the 2 years before baseline (yes/no).
Differences in drain fluid volume and pain between breasts were analysed using a paired Wilcoxon signed-rank test.
The number of overlapping SNPs between the two datasets is small for both ER-positive and overall breast cancer analyses.
To help redress the lack of risk factor information, we have conducted a case-control study of breast cancer, analysing associations with a large set of exposures.
In human breast tumors, analyses comparing genome copy number aberrations with gene expression signatures have revealed distinct genomic patterns that correlate with tumor subtype [ 26- 28].
