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Life span, Mr. Vaupel explained, has improved since 1840, with most scientific breakthroughs until 1950 favoring the young.
But there will be no big breakthroughs until the bigger problems of informality (in India), discrimination against migrants (China) and cronyism (everywhere) are dealt with.
Although it governed as a junior partner with Fine Gael in 1973 77 and 1981 87 (except for a period in 1982, when Fianna Fáil was in office), it made no electoral breakthroughs until 1990, when Mary Robinson, candidate of the Labour Party and the Workers Partyy, won the 1990 presidential election and became the first woman president of Ireland.
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Despite his numerous credits, Firth did not receive his major breakthrough until he appeared as Fitzwilliam Darcy in the television miniseries Pride and Prejudice.
His art doesn't have a big breakthrough until after the period the book covers - not really till after his death.
Saints hit the post and the bar in the first half but did not get the breakthrough until the 77th minute when MacLean headed in after good work on the left by the substitute Nigel Hasselbaink.
Yet some experts think that the central bank's assessment is overly optimistic and that it is too early to speak of a breakthrough; until a country activates the bond-buying program, there is no proof it will work as intended.
There seemed no likelihood of a breakthrough until a moment of resourcefulness from Vuckic.
Linfield had struggled to make the breakthrough until Thompson took full advantage of Magee's slip in midfield.
Nigel Clough's side struggled to find a breakthrough until John Brayford escaped down the right to tee up Murphy for the equaliser.
Barcelona dominated possession and territory against their city rivals, but did not make a breakthrough until Sanchez tapped in Neymar's low cross.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com