Sentence examples for breakthroughs defined from inspiring English sources
By 2025, when Tanzania aims to achieve the major development breakthroughs defined in its national Vision, the country's adolescents will be between 25 and 35 years old".
Patients who experienced HIV-1 RNA breakthrough (defined as HIV-1 RNA values between 50 and 1000 copies/mL by Roche Amplicor Ultrasensitive Assay) during the study period could receive intensification with efavirenz 600 mg once daily.
Here, breakthrough is defined as the time needed for the plume to achieve a pH mid-point between the ambient and the CO2 affected groundwater at the monitoring well.
In our study, breakthrough was defined clinically and/or radiologically by the patient's MS specialist.
Viral breakthrough was defined as a persistent (two consecutive determinations) on-treatment increase in serum HBV DNA level of >1 log10 copies/mL above the nadir level [ 12].
Nocturnal acid breakthrough was defined as the occurrence of intragastric pH < 4 for more than 1 h from 10 00 pm to 08 00 am [ 20].
Viral breakthrough was defined as a patient having HCV RNA ≥LLOQ during treatment after having previously had HCV RNA
Virologic breakthrough was defined as having either two consecutive HBV DNA values ≥400 copies/mL after having been <400 copies/mL or two consecutive HBV DNA values >1 log10 copies/mL from nadir.
Survival analyses were performed on two separate patient cohorts: the entire ICU cohort and the subset of patients in whom fluconazole was the sole initial antifungal therapy during the initial 72 hours of therapy (but exclusion of patients with breakthrough infection, defined as occurrence of candidaemia more than 72 hours prior to collection of the first positive blood culture).
