Sentence examples for breakthrough trials from inspiring English sources
According to Dr. Michael A. Caligiuri of The Ohio State University Comprehensive Cancer Center, this has resulted in multiple breakthrough trials and FDA approval of ibrutinib, another drug used to treat CLL.
10 Moving from metastatic settings to adjuvant, the study by Moertel et al 11 was the first breakthrough trial which showed survival advantage in patients with stage III colon cancer with fluorouracil plus levamisole.
In the late 1990s, breakthrough clinical trials of shorter and less expensive ARV regimens a short course of azidothymidine (AZT) for the mother or a single dose of Nevirapine to mother and infant demonstrated reductions of about 50% in vertical transmission of HIV [ 5, 6].
Some of them, liberated from stale institutions and ways of seeing, make breakthroughs by trial and error and collaboration.
Immersing themselves in Fleetwood Mac and CSNY, they then created their breakthrough LP The Trials of Van Occupanther, a gorgeous mix of soft rock, folk and prog, with a kind of Walt Whitmanish American quest narrative running through it like a logging route.
His atheism doesn't emerge as the breakthrough of a spiritual trial or of combat with an angel any more than his drive to video-record his surroundings are defined by any clearer motive than the mnemonic.
Some changes include the adoption of operational diagnostic criteria and psychometrics as well as assimilation of novel breakthrough methods of clinical trial research.
Of note, the incidence of breakthrough IFIs in our trial was unusually low compared with other published studies.
Representing thousands of victims, he achieved numerous trial breakthroughs.
The identification of a rapidly evolving population of CRF01 AE variants should be considered when designing new candidate vaccines and when evaluating breakthrough strains from current vaccine trials.
The FDA designated the immunotherapy drug pembrolizumab -- to be marketed as Keytruda -- a "breakthrough therapy" after early clinical trials suggested it might offer "substantial improvement over available therapies" for melanoma.
