"breakthrough is needed" is correct and usable in written English.
You could use this phrase when talking about a situation or problem that needs a fresh, new approach, or a new solution. For example: "We've been trying for months but no progress has been made - it looks like a breakthrough is needed if we're going to solve this issue."
In the short term, the outlook for the Doha round of global trade talks, where a big breakthrough is needed by the end of this year, will be coloured by CAFTA's fate.
To insure that both biodiesel and ethanol become more competitive in the marketplace, Wyman says that a key breakthrough is needed to make diesel fuel or other products such as ethanol competitively from sugars.
David Lloyd may have a famous name, but, having turned 24 last week, he hasn't had the opportunity to build up much in the way of famous deeds yet, particularly as he is one of those bits and pieces players who goes up and down the order and gets tossed the ball when a breakthrough is needed.
In his view (which he admitted is based on intuition), at least one more major breakthrough is needed before artificial intelligence reaches "the kind of human level intelligence that everyone has in this room, let alone get past it".
As our numbers only grow, a serious breakthrough is needed.
Seeing as cell-based systems can be quite time-consuming and labour intensive, and that no cell-free technique can be used exclusively to detect the oligomeric form of amylin, it is quite evident that a breakthrough is needed in development of a technique that would allow efficient screening of potential inhibitors of amylin-mediated cytotoxicity.
How this breakthrough was needed for a wilting England attack – all bar Mark Wood, that is, whose career-best four for 60 included Darren Bravo and the dangerous Shimron Hetmyer in the space of three balls.
Although enzyme applications are being developed in full swing, breakthroughs are needed to overcome their weaknesses in maintaining activities during the catalytic processes.
In particular, research breakthroughs are needed in the design and synthesis of biocompatible nanocarriers that enable the controlled delivery of drugs and vaccines — preferably in an oral manner — as well as the targeted delivery of immunotherapies.
