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The breakpoints were located on 6p25 and 6q26-27 and the deletion was estimated to be 1.3 Mb on the short arm and 6.7 Mb on the long arm.
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However, since the breakpoint was located on nucleotide 4755, the genomic segment to the right of the breakpoint was only composed of 150 nucleotides.
The recombination breakpoints were located in the gp120 C2 region in 12 of the 13 recombinants.
The remaining ten breakpoints were located in the LCR-poor distal fragment of 17p.
All breakpoints were located, and their positions are shown in Figure 2A.
The array CGH indicated the regions of chromosome 16 at which the breakpoints were located.
Further analysis showed that the four rearrangement breakpoints were located within the IS elements.
From this we conclude that the two breakpoints are located within distinct introns of the NBPF1 gene.
According to the array CGH data the two breakpoints are located between RP11 247C02 and RP11 672A20 (proximal breakpoint) and RP11 758J16 and RP11 745I11 (distal breakpoint).
For all the inversions, the proximal breakpoints are located within the heterochromatin.
Specifically, for each generated copy number profile, we know where the true breakpoints are located.
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