Both breakpoints were found to be enriched for low copy repeats, which, according to the Segmental Duplication Database (http://humanparalogy.gs.washington.edu/), share a 49.9 kb segment with 95% sequence similarity (no.9417), and the proximal breakpoint coincided with published DNA copy number variants.
The breakpoint value can be seen as a measure for the rewarding value of the reinforcer [61], and breakpoints were found to decrease with decreasing nutritional value of a food reward whereas they increase during food deprivation [61], [62].
Evidence for recombination breakpoints was found in all three islands and therefore the phylogeny for each non-recombinant block within the islands was analyzed independently.
In the other two families, no homologous sequence flanking the breakpoints was found, but the distal breakpoints were embedded in novel low-copy repeats, suggesting the potential involvement of genome architecture in stimulating these rearrangements.
Further telomeric, 11q breakpoints are found in many cancers.
No evidence was found for different integration site breakpoints in the genome between individuals within an interval.
Surprisingly, a slight negative association was found for ISS scores above this breakpoint.
When both rearrangement breakpoints matched a copy number breakpoint, the sum of the distances between the rearrangement and the copy number breakpoints was below 400kb, and when for only one rearrangement breakpoint a corresponding copy number breakpoint was found, the distance between both breakpoints was below 20kb.
A single breakpoint was found at position 567 by GARD.
In contrast, a breakpoint was found when a similar procedure was applied to the malaria incidence time series, on December 2002 955% confidence limits September 2001 February 2004), as shown by the minimization of BIC for one breakpoint in Figure 3B.
