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Such recombination bins between two adjacent recombination breakpoints were defined as single "bin markers".
Evolutionary breakpoints were defined as the limit between each adjacent human homologous region.
Breakpoints were defined as a set of coordinates on the genome spanning the genomic sequence of the deletions.
For comparative purposes, two scenarios were built for beta-lactams and for azithromycin: 1) aggressive pharmacodynamic breakpoints were defined as requiring 50% fT > MIC for all beta-lactams and total AUC/MIC ≥ 25 [ 22] for azithromycin; 2) conservative pharmacodynamic breakpoints were defined as requiring 30% fT > MIC for all beta-lactams and total AUC/MIC ≥ 10 [ 23] for azithromycin.
For comparative purpose, bactericidal pharmacodynamic breakpoints were defined as 40% f T > MIC for meropenem and imipenem, 50% f T > MIC for cefepime, and piperacillin-tazobactam, and a total drug AUC/MIC ≥ 125 for levofloxacin.
Breakpoints were defined as windows of 400 bp, the smallest size of any detected CNV, surrounding the inferred breakpoint position to account for the imprecision in determining the exact location.
Similar(53)
A sequence of consecutive CNA probes with no breakpoints is defined as a CNA unit, denoted by u (k, L) with k being the starting probe index and L being the length of the CNA unit.
The PK PD breakpoint was defined as the MIC at which the calculated target attainment was ≥95%.
The breakpoint was defined as the last ratio completed before the response was disrupted.
Breakpoint was defined as the number of presses contained in the last, successfully completed ratio in either a 1 hr session or after 15 min of non-responding, whichever came first.
If an intergenic region was determined to contain a breakpoint, the breakpoint was defined as the entire intergenic region.
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