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This study confirms the good correlation between GFAP breakdown product levels and CT scan findings in TBI patients [ 87].
GFAP breakdown product levels are able to differentiate TBI patients from uninjured controls with an AUC of 0.90 (95% CI = 0.86 to 0.94) and differentiate TBI patients with a GCS of 15 from normal controls with an AUC of 0.88 (95% CI = 0.82 to 0.93) [ 86].
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"Evidence suggests that exposure to DDT and its breakdown product DDE at levels substantially lower than that experienced in communities that use IRS may be associated with breast cancer, diabetes, spontaneous abortions, decreased semen quality, and impaired child neurodevelopment".
Inflammation was assessed by measurement of nitrites (nitrite, a breakdown product of nitric oxide), prostaglandin-E2 levels and cellular infiltration in the pouch fluid exudates.
Other evidence includes reduced levels of a breakdown product of serotonin, 5-Hydroxyindoleacetic acid, in the cerebral spinal fluid.
Peroxides of polyunsaturated fatty acids generate malondialdehyde (MDA), the most abundant aldehydic lipid breakdown product [ 19] that indicates the levels of stress and injury to the functional membrane.
Black tea consumption increases serum levels of tryptophan breakdown product kynurenine.
Creatinine is a breakdown product of muscle metabolism; serum creatinine levels are influenced by the muscle mass of the study participant.
It is common to see an increase in serum ALP activity and subsequent DPD (deoxypyridinoline, a breakdown product of collagen during bone resorption) level in response to ovariectomy [ 28].
Plasma was separated by centrifugation, and the levels of the PGI2 breakdown product, 6-keto-PGF1α, were determined by ELISA (Cayman Chemical).
In line with this, the protein level of αII-spectrin breakdown product in the diaphragm was significantly increased in CMV group compared with the CON (Fig. 4).
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