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Moreover, study of gene-manipulated animals that develop systemic autoimmune diseases has provided insights into the mechanisms of maintenance and breakdown of self tolerance.
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A total breakdown of self-control is the perfect backdrop for this bill.
Table 1 provides a breakdown of self-reported concussion based on playing position.
Systemic lupus erythematosus (SLE) is an autoimmune disorder characterized by a breakdown of self-tolerance in B cells and the production of antibodies against nuclear self-antigens.
However, pollen from other species can lead to a breakdown of self-incompatibility resulting in autogamy.
Mutations in AIRE cause APECED syndrome, which is characterized by a breakdown of self-tolerance.
This has become an attractive candidate mechanism for breakdown of self-tolerance in autoimmune diseases.
Inadequate clearance of apoptotic cells by macrophages is one of the reasons for the breakdown of self-tolerance.
Another possibility is that an impaired response to an infectious agent and delayed clearance could promote the breakdown of self-tolerance and the subsequent development of autoimmunity.
The perception of no longer being independent or having positive emotional attitudes as before led to a breakdown of self-image, thus changing the personalities of the women.
Breakdown of self-tolerance in the periphery (after exit from the bone marrow) during B-cell development and survival has also been reported to lead to autoimmunity.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com