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Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix.
Cervical softening is the product of complex modifications that include increased proteoglycan-to-collagen ratio, increased hyaluronic acid and water content, and breakdown of collagen by matrix metalloproteases.
The difference in total Hb is likely because of stromal angiogenesis, whereas decreased scattering can be attributed to breakdown of collagen network in the cervical stroma.
These findings suggest that the release of MMP-I in response to initial seeding on SIS and subsequent breakdown of collagen fibers is the mechanism responsible for an increase in mechanical compliance.
Matrix metalloproteinases, produced by neutrophils, macrophages, and fibroblasts in the wound, are responsible for breakdown of collagen.
It also slows the breakdown of collagen, Farris says, which is important in giving skin its youthful appearance and elasticity.
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Oncostatin M contributes to the release of proteoglycans and the breakdown of collagens [ 37].
TGF-β inhibits the expression of MMP-1 and MMP-3 by binding to a certain cell surface receptor complex (TGF-β receptor proteins: TβR I/II/III), thus preventing the breakdown of collagens.
First isolated (1902) from gelatin, a breakdown product of collagen, hydroxyproline is one of several so-called nonessential amino acids; i.e., animals can synthesize it from glutamic acid and do not require dietary sources.
Another potent inhibitor of angiogenesis is endostatin, which is a breakdown product of collagen XV111 [ 28*].
The final breakdown products of collagen include free and peptide bound hydroxyproline which are not reutilized for collagen biosynthesis (Reddy et al. 1991).
More suggestions(17)
rupture of collagen
disruption of collagen
distribution of collagen
breakdown of everything
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breakdown of agitation
breakdown of science
breakdown of law
breakdown of control
breakdown of morale
breakdown of communication
breakdown of usage
breakdown of sense
breakdown of student
breakdown of support
breakdown of engineering
breakdown of procuticle
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