Sentence examples for breakdown of brain from inspiring English sources
Taking the above caveats into account, the present behavioural, MRI and VBM data together allow certain conclusions to be drawn about the breakdown of brain organization for pain and temperature processing in these neurodegenerative diseases.
In a single published study in which the Lyme spirochete was incubated with human astrocytes, the authors found a significant up-regulation of MMP-9 (matrix metalloprotease 9), which may play a role in the breakdown of brain barriers (Perides et al., 1999).
The nature of the neuropsychological deficits in degenerative disorders offers a perspective on the breakdown of brain knowledge stores that is complementary to the study of acute focal lesions: whereas lesions such as stroke typically disrupt access to stored information, degenerative disorders such as semantic dementia affect knowledge stores proper (Jefferies and Lambon Ralph, 2006).
People who regularly fly long-haul have been shown to suffer from poorer brain function, thought to be caused by the breakdown of some brain structures, caused by the over-production of stress hormones.
Thus, breakdown of the brain's immune system may be an important factor in the development of neurodegeneration.
Breakdown of these brain rhythms in neuropsychiatric disorders, such as schizophrenia, depression and bipolar disorder, is thought to involve a defective GABA system.
First, pasiflora1 and pasiflora2 mutants exhibit all the characteristic phenotypes associated with disrupted SJs: breakdown of blood-brain and tracheal barriers, overelongated dorsal trunks, and SJ mislocalization in a variety of tissues.
It is also possible that inflammatory cytokines within the blood contribute to brain injury after SAH; the breakdown of the blood brain barrier after SAH could allow serum cytokines to enter the brain parenchyma leading to tissue injury there.
Thus, we could hypothesize that a dysregulation of astrocytes function in ALS pathology could result in a higher efflux of iron in the brain or that the breakdown of the blood-brain and blood-spinal cord barriers could be responsible for iron accumulation in central nervous system [ 38].
Since there is no evidence that there is breakdown of the blood brain barrier at or that virus is transported across the blood brain barrier these data strongly suggest that virus enters and replicates in the brain during the earliest period of acute infection in the peripheral blood.
