Sentence examples for breakdown of alcohol from inspiring English sources

To back up her hunch, Hines looked at ADH3, a gene responsible for the breakdown of alcohol by oxidation.

In humans and rodents, genetic factors may explain tolerance to ethanol [48] [49], Variation in expression of alcohol dehydrogenase and aldehyde dehydrogenase, the primary enzymes involved in the breakdown of alcohol, is a good predictor of individual tolerance of ethanol.

The oxidative breakdown of alcohol by dedicated alcohol dehydrogenases and by cytochrome P450 monooxygenases generates ROS that may damage proteins, lipids, and other cellular structures.

Acetaldehyde generated during the oxidative breakdown of alcohol inhibits certain immune cells (i.e., natural killer cells) that normally moderate fibrosis by inducing apoptosis in activated hepatic stellate cells (HSCs) (Hernandez-Gea and Friedman 2011; Orman et al. 2013).

There seem to be a few things at work: gastric irritation; the effects of the acetaldehyde (the main breakdown product of alcohol), which is extremely toxic; tiredness.

By holding down blood alcohol, nicotine may spur excessive drinking, and yet not suppress levels of harmful breakdown products of alcohol like acetaldehyde, which can damage the liver and heart.

Of course one of the main proposed reasons that you feel so rough after excess alcohol consumption is the breakdown products of alcohol itself.

It is upregulated in macrophages (i.e., Kupffer cells) as well as in circulating monocytes in response to Toll-like receptor 4 (TLR4) activation by bacterial endotoxin (i.e., lipopolysaccharide [LPS]) and by the breakdown products of alcohol, acetaldehyde and acetic acid.

Furthermore, only one study [ 45] had provided a breakdown by frequency of alcohol use: "daily", "weekly", and "monthly" (however, the amount consumed was not reported).

Below is a breakdown of just how alcohol takes a toll on your body and mind, making you look and feel older than you should ― plus some advice on how to cut back but still cut loose.

Many years and a dozen wars between Bruno and I had passed since then, as well as endless phone calls, three miscarriages, much of what the French call malentendu, break-ups, a breakdown, and a lot of alcohol.