Sentence examples for breakdown in models of from inspiring English sources

Moreover, a selection of the drugs used have relieved the neurological deficits and prevented BBB breakdown in models of EAE.

Similar findings were shown to be associated with the brain regions most affected by BBB breakdown in models of transient middle cerebral artery occlusion as well as metabolic inhibition [ 43, 44].

Studies have also suggested that BPA interferes with germ cell nest breakdown in animal models.

The extent of agglomerate breakdown in a model agglomerate/matrix system was compared after processing by z-blade mixing followed by ram extrusion and by a co-rotating twin-screw mixing/extrusion process at various operating parameters; the latter process was found to be more effective at breaking down the agglomerates under all processing conditions.

While the hypothesis that grain (1,3 1,4 -β-glucan 1,3 1,4 -β-glucan 1,3 1,4 -β-glucan synthesise (1,3;1,4)-β-glucontentpersuasise, it is equally valideterminedelic variation in genes involved in the byeakdown or re-modellingenes(1,3;1,4)-β-glucan could also be responsible.

Consistent with in vitro models, CNS vascular permeability coincides with alteration of CEC tight junctions in rodent models of BBB breakdown [3], [14] [16].

Our data suggest a model whereby CD4+ breakdown in the absence of viral challenge is associated with compensatory pathway(s) at the level of bone marrow stromal cells, resulting in increased IL-7 production and activated Stat5 signaling, specifically in CD4+ T cells.

If there is a fundamental breakdown in the business model, we will sell.

Thus, experimental models are needed to better characterize ALS-associated vascular dysfunction and determine whether exacerbating or mitigating the BSCB breakdown and erythrocyte extravasation in accepted experimental models of ALS contributes to motor neuron injury and disease progression during ALS pathogenesis.

We used Foxp3DTR mice to attempt local depletion of Foxp3 + cells in the lung in a model of tolerance breakdown.

Recent studies in various animal models of neuroinflammation have confirmed breakdown of the BBB in a cytokine/chemokine-dependent manner [ 31- 33].