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The overexpression of CCL2 alone was therefore insufficient to produce BBB breakdown, defined in this study as a disruption of the endothelium and glia limitans.
BBB breakdown, defined as a disruption of both the endothelium and glia limitans, was found only in CCL2 transgenic mice following PTx administration and seen on MR images as focal areas of contrast enhancement and histologically as dextrans leaking from blood vessels.
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The mean-field breakdown limit is defined in terms of a microstructural correlation measure (characteristic dislocation bow-out length) below which the local availability of dislocation sources and not the density of GNDs dominates the mechanical size effect.
These are all indicators of "team breakdown", inadequately defined and co-ordinated roles, and poor communication (Paton et al. 1998a, 1999).
Resistance after breakdown is defined as Figure 4 I-V characteristics from V G = 0 to -15 V in linear scale for SH/O and H/O.
In general, a breakdown is defined when the speed decrease between two consecutive time intervals exceeds a pre-specified threshold, and this lower speed is sustained for a predefined length of time [18].
The breakdown for defined benefit pensions is much more even.
In contrast, in higher perceived risk areas (shorter testing intervals), the risk of breakdown is defined by the history of disease and the probability of badger occurrence.
By the time she died, at fifty-eight, in October of 1950, she had reduced her abject dependence on narcotics, though even after several hospitalizations for alcohol- and drug-related nervous breakdowns she defined sobriety as restricting her daily liquor intake to a litre and a half of wine.
"Climate and ecological breakdown will define the life of every child and student alive today.
As one data source, ISO drawings provide the basis for performing work breakdown and defining all the fabrication activities.
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CEO of Professional Science Editing for Scientists @ prosciediting.com