Repair practices are analyzed in terms of who initiates: the interactant/s (self-initiation) or someone else (other-initiation) and who repairs the breakdown (in the context of the cooking activity, the completion of the step demonstrates repair and a solution to the trouble).
We can describe the multifaceted details of our primary outcome but we cannot further breakdown exactly which contexts and mechanisms contribute to each facet.
Any communicative breakdown in such a context can prove problematic for the speakers.
Neither John McCain nor Barack Obama has addressed this great humanitarian breakdown, except in the context of political squabbling.
Although it is easy to isolate those social breakdowns from their surrounding context and interpret them solely as evidence of a lack of Confederate morale, in fact the contours of Confederate society were shaped — partly but effectively — by Union policy.
Kristol's essays of forty years ago, set in the context of social breakdown and the ongoing spectacle of left-wing lunacy, make the move of liberal-minded intellectuals to the right entirely understandable and, in some ways, justifiable.
Alastair Sooke suggests that perhaps, in the context of the breakdown of Lichtenstein's own marriage, these paintings were closer to a 'revenge fantasy', that these women were how he wished the women in his own life would behave.
Practical consequences of this breakdown are illustrated in the context of the calculation of the effective dosage of enzyme inhibitor drug needed to suppress intra-compartmental enzyme activity by a given amount.
Reductions in NAA/creatine are reflective of neuronal loss and/or dysfunction, alterations in myoinositol/crea tine are suggestive of glial activation or damage, and modulation of choline/creatine can provide important information on membrane phospholipids in the context of myelin breakdown.
In order to modulate drug action, it follows that a detailed mechanistic understanding is required of the molecular factors that control the rate of enzyme inhibitor complex formation and breakdown, which in the current context is slow relative to many of the common motions associated with biological macromolecules.
