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Multiple regression modeling was used to develop two models for the granule size: an empirical model, based on the four process parameters, and a fundamental model, based on the balance between the granule growth affected by the theoretical powder bed moisture content and the droplet size and the breakage effect of the airflow rate.
The DNA breakage effect was more pronounced in the mutant cells, especially in the bub1 and tel1 cells compared to the haploid wild type (Fig. 6b).
We have shown in Figure 7 that the DNA breakage effect of TQ is inhibited in the presence of copper-specific chelators in comet assay, thus in order to verify that the cytotoxic action of TQ in cancer cells is also copper mediated, prostate cancer cell lines PC3 and LNCaP were treated with 5 μM TQ in the presence of metal-specific chelators.
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A comparison of the detection capacity of assays sampling different kinds of genetic damage revealed that various substances are highly effective in inducing mutations but do not produce chromosome breakage effects at all, or only at much higher concentrations than those required for mutation induction.
The coalescence and breakage effects of the gas bubbles are modeled according to the coalescence by the random collision driven by turbulence and wake entrainment while for bubble breakage by the impact of turbulent eddies.
To examine the possible involvement of iron and zinc in TQ-induced DNA breakage, the effect of desferrioxamine mesylate (a Fe(II -specific chelator) and hII -specificzinchelatoric chelandr) histidineexamined on DNA breakage in lymphocytes and lymphocyte nuclei.
Therefore, the effect of the compression force rate on the breakage force of salt and glass spheres is examined to check the limit of the quasi-static region.
A specially designed apparatus, named single-event fluid mill, was employed to experimentally estimate those two breakage functions of the elementary breakage event with a breakage rate correction factor θ. The classification effect is taken into consideration by defining a cutting size under which the particle will not break any more.
However, studies based on larger number of randomly distributed molecular markers of different types will provide a more detailed picture of the distribution of deletions along the length of the chromosome, and will help to determine, whether or not, the radiation-induced breakage is effected by chromosome structure or any other biological phenomenon.
The root causes of the lead breakage and dominant effecting factors are identified through various tests and simulations.
A reliability model was developed for the calculations of the probability of pipe breakage associated with transient effect.
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