True mechanical instability may result from loosening, bone loss, prosthetic breakage, component size or position, fracture, wear, or collateral ligament failure.
Features associated with pathology include: radiolucent zones (> 2 mm), periprosthetic fractures, endosteal scalloping, hardware breakage, component wear, heterotopic ossification, subluxation, dislocation, or soft-tissue masses or fluid collections (Roth et al. 2012).
We performed a search using the keywords "ceramic", "alumina", and "total hip replacement/hip prosthesis" in combination with "failure", "fracture", "debris", "diagnosis", "revision surgery", "component breakage", "head", and "risk factors" with no limit regarding the year of publication.
"Death and breakage is part of the system".
Breakage of the tibia component was therefore relatively common in our series, but apart from that we do not have explanations for the poor survival rate.
It is useful to determine storage conditions and to set inspection before use for single-use component, because breakage or contamination with insoluble visible matter and component interconnections may sometimes be difficult to detect at the time of receipt or may occur later during unpacking or storage.
Here we show that nuclei which conserve their structure, internal compartmentalisation, and transcriptional activity can be isolated in media which contain an inert, volume-occupying polymer to replace the cytoplasmic macromolecules which are dispersed upon cell breakage, with no ionic components other than 100 µM K-Hepes buffer.
None of the implants needed revision for any reason, none of the cups were considered to have failed, no dislocations nor breakage of the ceramic components were recorded.
During the cement production process, gypsum and other additives are input in the clinker grinding and each component present different breakage characteristics.
The Nbs1 protein, hypomorphic mutant in Nijmegen breakage syndrome (NBS), is a component of the Mre11/Rad50/Nbs1 (M/R/N) complex that acts as a DNA double-strand break sensor and functions in cell cycle checkpoint in response to DNA damage and DNA repair.
Malalignment of the acetabular cup may lead to dislocation (Jolles et al. 2002, Shon et al. 2005), accelerated wear or breakage of the bearing, and component loosening (Kennedy et al. 1998).
