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We took it in turns to break trail, an exhausting process that simultaneously saps your will to live and makes you feel like Sir Edmund Hillary.
Chuckling, he said, "I'd just like enough people to use it so that I don't have to break trail every time I ski".
The leading mushers had to break trail because the snowmobile intended for the task broke down.
He organized a vanguard company to break trail to the Rocky Mountains, evaluate trail conditions, find sources of water and select a central gathering point in the Great Basin.
Thus, combined downregulation of cFlip and Mcl-1 is sufficient to break TRAIL resistance.
However, combinatorial treatment with sensitizing agents can break TRAIL apoptosis resistance resulting in synergistic and selective killing of tumor cells.
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Despite their dominance, Portugal were actually lucky not to head into the break trailing.
The top-ranked Williams, seeking her sixth Key Biscayne title and her first since 2008, was down a service break trailing by 4-1 in the second set before she won five straight games.
The Blazers, a league-best 18-3 since the All-Star Game break, trailed by 10 at the half but got back into it by taking advantage of a balanced scoring attack and cold shooting by the Timberwolves.
Twelvetrees' conversion meant Gloucester were right back in it at the break, trailing only 10-7, and they exploded out of the blocks in the second half.
Welsh, who also lost Nathan Trevett to a yellow card before half-time, went into the break trailing by just three points with Reynolds going in under the posts.
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