Exact(5)
All these nine introns are in positions that do not break the reading frame (phase 0 introns).
The typical intron/exon structure of most tetraspanins has been reported, in bilaterian animals, to consist of six introns in positions that do not break the reading frame (so called phase 0 introns) that we have named introns 1 to 6 (Fig. 1 B) [40].
Though skipping of the LNK pair may break the reading frame, the low abundance of this defective transcript will probably not cause severe loss of overall product activity.
The read-back of the testimony began at 6 p.m. Outside of a 45-minute dinner break, the reading lasted until roughly 10 p.m.
We also observed that of the ten more highly derived intron positions we detect in this study, seven break the reading frame (either phases 1 or 2), in contrast to the ancestral nine phase 0 well-conserved introns (introns 1 through 6).
Similar(55)
Due to the fact that any detected changes in the structure of RT sequences in T. szidati are incapable of coding for a functional reverse transcriptase (breaking the reading frame of RT), we can refer the elements of each of the three groups to pseudogenes, derived from the RT protein-coding gene.
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Tophat perform the mapping by breaking the read into shorter fragments and map each fragment independently.
On the other hand, the de Bruijn graph approach (Compeau et al., 2011), which breaks the reads into k-mers and then constructs a de Bruijn graph on these k-mers, is difficult because of the mixture of genomic sequences from many species and the higher rate of NGS sequencing errors.
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