Sentence examples for break marker from inspiring English sources
We next evaluated the level of endogenous DNA damage in Nbn CNS-del neocortex by immunohistochemical analysis on a DNA strand break marker, phosphorylated H2AX (γH2AX).
There was also evidence of a DNA damage response (γH2AX blot in Figure S6B), backed up by staining of cells and skin for the double-strand break marker γH2AX.
Consistent with the above observation, the number of cells, which were positive for γH2AX (a DNA double-stranded break marker), Sycp3 (a main component of synaptonemal complex) and MLH1 (a crossover associated gene), were dramatically decreased in RHAU knockout testes.
We quantitated the number of TIFs, as visualised by the presence of the DNA double strand break marker phosphorylated histone H2AX (γ-H2AX), at telomere ends in HeLa and HT1080 vector and hTR cells at pd 220 and pd 300.
They are also characterised by high immunohistochemical expression of TP53 (expression level between 80% and 92%) and highly positive levels for proliferation marker Ki67 and DNA double-strand break marker γ-H2AX [ 43– 43].
Next, we analyzed their activation pattern and in H125 bulk cells, pDNA-PK (pS2056), pATM (pS1981), as well as the DNA double-strand break marker γH2AX (histonetone family, member X; pS139) were all increased after IR and after bleomycin treatment.
H3K56 acetylation level increases during S phase and in DNA damage foci, colocalizes with double-strand break markers, such as γ-H2AX, pATM, CHK2, and p53.
The increase of ROS level in nucleus results in the activation of ataxia telangiectasia mutated (ATM), as well as ataxia telangiectasia and Rad 3-related (ATR) kinases that induce the p53-mediated apoptosis and account for the increase of DNA double-strand breaks marker (γH2AX) level.
He failed to score in his following three games as frenzied fans followed each contest in anticipation of the record-breaking marker.
Histamine significantly alleviated histological damage, reducing lipid peroxidation, serum creatine kinase-myocardial band activity and expression of DNA double-strand breaks marker γH2AX.
A DNA double strand break (DSB) marker, γ-H2AX foci, and a DSB repair marker, phosphorylated DNA-PKcs focincreasedsed in number when non-irradiated cells reached several passages before senescence.
