Sentence examples for break induction from inspiring English sources

Anti-γH2AX immunolabeling was used to investigate both DNA double-strand break induction and repair rates in endothelial cells.

We can also not exclude that the use of radiomimetics may result in different results compared to double strand break induction by ionizing irradiation.

Therefore, we explored whether the gene trap deleting the last C-terminal BRCT domain interfered with foci formation following DNA double strand break induction.

Higher SHR stimulation by bleocin is likely due to its pronounced single and double strand break induction [48] compared to paraquat-induced accumulation of ROS species mainly in chloroplasts [49].

Thus, restart via nucleases and break induction fails and forks collapse.

Upon DNA double-strand break induction H2AX becomes rapidly phosphorylated around the damage site, forming nuclear foci that typically contain thousands of histone molecules.

For I-SceI-break induction, individual colonies were grown overnight in glucose medium before dilution 1 10 into raffinose-containing medium.

Thus, the observed increase in DNA migration in comet assay could be explained by either base damage or strand breaks induction by ROS generation or by direct action of TTHL on DNA.

Time indicates the observation interval in minutes including double strand break (DSB) induction (0 60 min) and recovery (60 180 min).

RecA is a multifunctional protein that is involved in DNA recombination, DNA double-strand break repair, induction of the SOS response, SOS mutagenesis and the repair of stalled replication forks [ 27].

Similarly, sea3 ∆ mutants exhibited a delay in colony formation in a BIR assay strain after double-strand break (DSB) induction as well as on the DNA-damaging agent bleomycin.