The expression breadth of population- and sex-biased genes was assessed by calculating τ (Yanai et al. 2005; Larracuente et al. 2008).
While the results from these studies provided tremendous insight into the genetic architecture of the disease, recent studies of non-European populations have shown utility in expanding the breadth of populations studied.
However, all these studies have some shortcomings with respect to the set of genes represented on the microarray, the breadth of the population genetic data provided along with the mCGH results, or the size and composition of the sample population.
Researchers have to weigh the trade-off of single cell read depth or single-cell population breadth.
A general issue in exploiting such approach concerns the breadth of the population that can be reached by serious games.
And if you look at other data sources, there's just no other data sources with that breadth across the population," says Polzer, discussing the advantage of attaching a big data business to carriers' heavily loaded pipes.
Genetic bottlenecks decrease the genetic breadth within a population, and a decrease in the diversity of both nonresponders and relapsers was observed, consistent with both groups passing through a bottleneck.
General transfer functions can also be used to estimate the breadth of a population's realized niche (Rehfeldt et al. 1999).
We quantify the degree of specialization by the number of ecotypes evolved and the niche breadth of the population, and observe that these are sensitive to resource influx and trade-offs.
We monitored evolution of attachment rate, the phenotype that governs diet breadth, in phage populations adapting to both low and high host density microcosms.
