Sentence examples for breadth of the response from inspiring English sources

However little is known about the breadth of the response induced by vaccines carrying multiple proteins.

Our simulation will help in the design of clinical trials in which the breadth of the response is being measured, by allowing a calculation for the minimum amount of blood that needs to be collected.

We found that the breadth of the response narrowed as the CD4 count declined and that, specifically, the contribution of Gag responses to the overall response decreased.

One possible way to increase the breadth of the response would be to include most or all of the HIV-1 proteome into a viral vector [5].

Thus we see that the relation between the avidity and the breadth of the response can be non-trivial and counter-intuitive.

The breadth of the response to MCMV in the B6 mouse provides an excellent tool with which to probe the nature of CD8+ T cell priming.

This result was expected, although the breadth of this response, i.e. the comprehensive recruitment of multiple and diverse immune signaling pathways in these lesion tissues was surprising.

We hypothesized that presentation of HIV envelope trimers presented in a physiological orientation on the surface of lipid nanocapsules might promote breadth of the humoral response, by enabling a more diverse pool of B-cells to be recruited into the immune response via multivalent engagement of particle-bound trimers.

76, 77 Depending on a host's infection or vaccination history, the immune response may focus on more or less conserved epitopes, creating individual differences in the breadth of the induced response.

The breadth of the antibody response was evaluated against subtype A, B, C, and D variants of HIV-1.

Thus, VLPs can be enriched with ISMs by protein transfer to increase the potency and breadth of the immune response, which has implications in developing effective nanoparticle-based vaccines against a broad spectrum of enveloped viruses.