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We identified a sampling frame that balanced breadth of sampling for general inference with sensible investment of resources on replication projects.
Strengths of the study include the breadth of sampling across the city and two stage methods.
First, the depth and breadth of sampling for oral microbiota have been insufficient in general, and the optimal parameters not determined for that of gingivitis patients in particular.
We are attempting to identify a balance of breadth of sampling for general inference with sensible investment of resources on replication projects to determine to what extent the included experiments are reproducible.
Nonetheless, the breadth of sampling is impressive, with members of 36 bacterial and archaeal phyla sequenced by the end of 2009, and the unequal representation of different lineages allows comparative studies to be carried out at shallow and deep levels.
We also agree the DU145 model, as well as the LAPC9 model, were important in contributing to the overall conclusions, however we are attempting to identify a balance of breadth of sampling for general inference with sensible investment of resources on replication projects to determine to what extent the included experiments are reproducible.
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The goal of inserting the MC step was to increase the breadth of sampled configurational space.
Our goal was to help fill this gap by doubling the number of fully sequenced plastid genomes and greatly expanding the phylogenetic breadth of sampled species.
Partial correlations were used to determine the relationship between geographic range and environmental breadth independent of sampling effort.
Furthermore, in striking a balance between privacy and data, it is also important to capture data that encompasses the widest possible demographic to ensure that we are sampling the breadth of samples as to not distort the results.
To this end, with exclusion of gnetophytes from data sets, tree-building method and breadth of taxon sampling no longer influence the placements of ginkgo, but the sequence type is a determinant.
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