Sentence examples for breadth of phenotypic from inspiring English sources

In many respects, a general survey of gene expression phenotypes serves as a proxy for the nature and breadth of phenotypic variation in human cancer [ 2, 3].

Laying the initial groundwork includes evaluation of the full breadth of phenotypic associations of highly replicated GWAS-defined variants and their allele frequencies on a population basis, particularly in populations of non-European ancestry.

The study described in this report builds on the large KOMP/EUCOMM resource of targeted mutations in mouse ES cells (Skarnes et al., 2011) and illustrates the breadth of phenotypic information that can be garnered from an organized effort.

The breadth of phenotypic data across the PAGE network and the inclusion of large samples from several ethnic/racial groups allow us to move beyond discovery toward characterizing each variant, by defining its epidemiologic architecture.

Hsp90's vast interaction network explains the breadth of its phenotypic reach, including Hsp90-dependent de novo mutations and epigenetic effects on gene regulation.

To take advantage of these tools, a core collection of 407 flax accessions capturing the breadth of the phenotypic diversity of the PGRC collection was assembled.

Our analysis indicates broad conservation of coding potential for transcriptional regulators, and the limited observed variation in the presence or absence of encoded regulators is unlikely to explain the breadth of observed phenotypic differences.

Our study aimed to define differences in clinical features between KAT6B variant-positive and KAT6B variant-negative patients, and to explore the breadth of the phenotypic spectrum, examining in particular, the clinical overlap between SBBS and GPS.

Additionally, the breadth and depth of phenotypic information and biological samples collected from participants is unparalleled by any other study in the Middle East and Asia.

In order to identify discriminatory SNPs, the genomes of 17 EMRSA-15 strains, selected to represent the breadth of genotypic and phenotypic diversity of EMRSA-15 isolates in Scotland, were determined and phylogenetic reconstruction was carried out.

Thus comparisons involving field and chamber-grown plants can provide novel and valuable insights into the breadth of traits subject to phenotypic plasticity and how they may contribute towards the adaptation of plants to their natural environment.