Sentence examples for breadth of pathways from inspiring English sources

The histological and molecular change of the gland during pregnancy can be appreciated by the increase in cross-section area and total DNA, as well as the breadth of pathways affected (Fig. 8).

Similarly to IL-2, TGF-β1 exerts multiple effects on different cell types and has not proven to be a clinically useful target to manipulate Treg cell differentiation, again pointing to the need to better understand the breadth of pathways involved.

This was useful in understanding the breadth of Makers' pathways and how they overlap with one another and intersect with engineering.

Such results strongly indicated that the HPV16 effectively affected a breadth of signaling pathways [ 13, 55, 56].

Furthermore, not only was HPV16 highly prone to interact with hub proteins and bottleneck proteins, but also it could effectively affect a breadth of signaling pathways.

Furthermore, our computational approaches suggest a framework to bin compounds into mechanistic classes, which holds particular relevance to future efforts to use polypharmacy to modulate the immune response by suggesting combinations that might target the maximal breadth of inflammatory pathways.

Identification of these predicted targets that are implicated in diverse biological processes expands the breadth of processes and pathways that are under miRNA regulation.

These efforts should greatly improve the breadth of genes to which pathway-based mutation impact approaches can be applied.

Selected sequences were chosen in order to obtain an overall breadth of diverse biological and molecular pathways.

Despite the breadth of molecules, genes and indeed pathways implicated in GC, there are a few that stand out and deserve mention.

Overall, these data confirm that multiple PRRs and downstream signalling pathways drive the breadth of cytokine and chemokine production by primary microglia in response to NSV (Table 1).