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Note that the organ-specificity index τ is inversely correlated with the number (breadth) of organs at which a gene is expressed.
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I choose to specialize in oncology because it involves a breadth of organ systems and because it possesses both scientific intrigue and emotional intensity; for this is one of the only professions in which one?s presence means so much to patients despite our inability to cure.
By combining diverse types of annotation, we can better understand the function of a given gene in a breadth of tissues and organ systems and of the biological processes it is involved in the organismal level, as well as its role in disease.
Although we do not have information on the actual bioactive metabolites that reach the target organs, the breadth of biological activities observed in the present study indicates that OPP is bioavailable in animals and triggers a central regulatory response, which modulates key metabolic functions.
To date, more than 25 manuscripts have been published using multiple years of the NIS that cover a breadth of healthcare topics, including solid organ transplantation [ 14- 17].
Producing visual images of organs.
Breadth of gene expression was estimated as the number of organ and tissue sources of gene-specific ESTs.
The breadth of expression of a gene (EB) takes into account the number of experimental units (organs or developmental stages) in which a gene is expressed.
For most of the genes in our list we could calculate the breadth of expression based on their expression levels collected across the developmental gradient in several organs of A. thaliana [ 136].
To compare the expression breadth of imprinted genes and their paralogs, we calculated two indices, expression width and organ specificity.
The interplay between Greg's organ and Ron Jackson on guitar is fantastic -- Monk is seldom played on guitar, and the breadth of his ouevre has not been previously tapped by an organist, either.
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