Sentence examples for breadth of genes from inspiring English sources
These efforts should greatly improve the breadth of genes to which pathway-based mutation impact approaches can be applied.
Finally, Foret et al. (2009) previously used an oligonucleotide microarray representing the honeybee OGS (Honeybee Genome Sequencing Consortium 2006) to assess the expression breadth of genes among the following tissues in Ap. mellifera: antenna, brain, whole-body larva, hypopharyngeal gland, ovary, and thorax.
The genome wide distribution of CNVs and the abundance and breadth of genes overlapping CNV regions, as well as their widespread involvement in local and distant gene regulation, indicate the extensive contribution of CNVs in phenotypic variation, similar to that observed in human studies [ 25].
Similar to Ka values, K3' values inversely correlated with breadth of gene expression (R = −0.11, p<0.01).
Breadth of gene expression was estimated as the number of organ and tissue sources of gene-specific ESTs.
In addition, we provide evidence that the level and the breadth of gene expression are related in opposite ways to many structural parameters of gene sequences.
The considered regional variables only partially accounted for the relationships between the level and breadth of gene expression and gene sequences.
We show that architecture of regulatory PK genes significantly differs from other protein coding genes and explore relationships between gene structure, evolutionary conservation, transcript levels and breadth of gene expression.
The level of non-synonymous substitutions in PK genes negatively correlated with breadth of gene expression (R = −0.82, p = 1.73×10−9, Figure 3A), which is consistent with a general trend for non-PK genes and correlations observed in protein coding regions of non-regulatory genes [26], [27].
These patterns confirm that the breadth of gene expression is a contributing factor to the evolution of nucleotide polymorphism.
Two important considerations in assembly analysis are the breadth of gene space coverage and the degree of coverage fragmentation.
