Exact(1)
A MAb elicited by 426 MCP demonstrates a similar breadth of binding to oligomeric gp120 on cells infected with viruses from different clades, and actually detects virus at a higher intensity and on more cells infected with a clade D isolate than does the MAb b12 (Table 5 and Figure 8).
Similar(59)
One way to increase the likelihood of a quorum is to increase the length or breadth of the ice-binding site through natural selection or protein engineering.
It is possible that the greater breadth of zinc finger protein binding may lead to differences in toxicity and carcinogenic potential.
To determine the binding breadth of R53 for HIV-1 gp120 from different clades, nine representative gp120s were tested: 92UG037.8 from clade A; 92US715, BaL, and JR-FL from clade B; 96ZM651 and 93MW965 from clade C; 92US021 from clade D; and 93TH976.17 and AE consensus from clade AE.
However, the breadth of antibody inhibition against different CSA-binding parasite lines was not examined, and overall there has been limited characterization of multidomain VAR2CSA immunogens.
Motif2 and motif3, which span the breadth of the protein, connect the substrate-binding surface to the opposite side of the protein.
Importantly, we have shown that the use of the particulate vaccine increased the breadth of the antibody response, as evidenced by binding antibodies produced to several conserved targets on the envelope structure, including the MPER seqeuence of gp41.
Nature of binding: None.
Choose the type of binding.
Interestingly, motif2 and motif3 span the breadth of the protein and connect the substrate-binding surface to the opposite side of the protein where potential electron donor proteins might interact.
To assess the degree to which these IgG cross-inhibit EPCR binding, they were tested against a set of 25 EPCR binding CIDRα1 domains, selected to represent the breadth of sequence diversity.
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