After the effects of expression breadth have been factored out, all non-coding region parameters are more strongly negatively related with Exp avg (Table 1).
Concretely, highly expressed genes are more compact than lowly expressed genes, which is more pronounced when the effects of expression breadth have been factored out.
The curvelinear relationships between gene structure characterisics and expression breadth have been taken as evidence supporting the conjecture of "goldden middle", stating that intermediately expressed genes are sorrounded by longest noncoding sequences because of complex regulations [ 24].
In the context of niche breadth, it has been shown that the Shannon-Wiener measure is most sensitive, while Hurlbert's and particularly Smith's measure are less sensitive for the selection of rare resources [ 21] (see also [ 20]).
Barzun's breadth of erudition has been a byword among friends and colleagues for six decades.
It's a diverse audience – scientists, artists, designers, journalists, activists and academics are all represented and the breadth of activity has been incredible.
And that fact has bedeviled economists' attempts to figure out just how important a half century's worth of economic integration, in breadth and depth, has been to the European economy.
"They see dispersal as a great thing, that it's better not to have a concentration or too much attention overinvested in one individual," said David J. Garrow, a Pulitzer Prize-winning historian who has written about the civil rights and women's rights movements".The speed and breadth of change has been just breathtaking," he added.
The issue of breadth and flexibility has been recommended by policy-makers and educators as a means of making the Ph.D. more adaptable and useful in a broader range of professions outside of academia.
