Sentence examples for breadth and potency in from inspiring English sources

The majority of infected individuals make "conventional Abs" that have limited breadth and potency in standard neutralization assays (2, 3).

Anti-V3 mAbs exhibited the most breadth and potency in neutralizing the evolving viruses.

Clinical proof-of-concept demonstrated by the first-in-class MI bevirimat and reappearance of second-generation drug candidates with improved breadth and potency in clinical trials strongly suggest that in the near future multiple MIs can be approved and used for treatment of HIV/AIDS patients.

Progressive modifications in their chemical structure have resulted in improved breadth and potency of in vitro activity and pharmacokinetics (1).

Since it is desirable to confer protective immunity in poultry and HA DNA vaccination was effective in mice, we next examined the breadth and potency of single or multiple HA plasmid immunization in chickens.

Further, these mAbs mediate potent plasma IgG-specific ADCC breadth and potency and contribute to ADCC activity in other HIV-infected individuals.

Although much is known about the role of variable domains in the neutralization breadth and potency of these bNAbs, the contribution of Fc domains to their activities is, by contrast, poorly characterized.

Structural and functional analyses reveal that somatic mutations in FWR residues enhance breadth and potency by providing increased flexibility and/or direct antigen contact.

Structural analysis of an HIV antibody reveals residues important for neutralization breadth and potency.

These findings suggest innovative strategies for generating biNAbs with enhanced neutralization breadth and potency, representing ideal candidate molecules for the control of HIV-1 infection.

Although HIV infection induces a vigorous Ab response in nearly all infected individuals, only ~1% produce Abs that can neutralize a wide range of HIV subtype Abs (1), and only ~10 to 25% of HIV-infected subjects produce cross-neutralizing Ab responses with moderate breadth and potency.