The results obtained from the case-study analysed clearly demonstrate that climate change combined with increasing urbanisation is likely to lead to worsening river water quality in terms of both frequency and magnitude of breaching threshold dissolved oxygen and ammonium concentrations.
One could argue the advanced degree of change in the social-ecological system of the Mara has left traditional ecological knowledge and local approaches to land stewardship in question, and perhaps reflecting a breached threshold of stability, or as Plummer and Armitage (2007) would call a system flip.
Algorithms, based on the symptom score, generated alerts if readings were omitted or breached thresholds.
"We have not cited names because we were looking at broader patterns of organisation and planning which breach the threshold of... war crimes and crimes against humanity..
Employers would pay NICs only on earnings above £80 a week, up from £62 now; and would no longer pay NICs on the first £80 once earnings breach the threshold.
An adopted sporadic case would need to be diagnosed at the age of ⩽24 years to breach the threshold using BRCAPRO.
Simulations of NAADP-dependent junctional Ca 2+ transients demonstrate that the magnitude of these signals can breach the threshold for CICR via RyR3.
Most importantly, our model shows that increasing the L-SR junctional width above 50 nm lowers the magnitude of junctional [Ca 2+] such that there is a failure to breach the threshold for CICR via RyR3.
This comparison underscores the important constraint played by the width of the L-SR junctions and indicates that, unless the membrane separation is kept below about 30 nm, it is not possible for [Ca 2+] NJ to breach the threshold for RyR3 Ca 2+ release.
Even within the variability of our recorded values of L-SR junctional widths and extension, our results suggest that localized [Ca 2+] transients due to junctional Ca 2+ release can without fail reach values required to breach the threshold for CICR from junctional RyR3s.
