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The degree distribution of giant network branches was computed using the formula P(k) = N k)/ N where N is the number of nodes and N(k) denotes the number of nodes with degree k [ 25].
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To demonstrate the visualization technique, blood flow through the aortic arch region and the three main arterial branches is computed using various Womersley numbers.
Approximate likelihood-ratio tests (aLRTs) for branches were computed using PHYML 3.0 with Shimodaira-Hasegawa-like support values (26 29; http://atgc.lirmm.fr/phyml/).
Branch support was computed using aLRT (approximate likelihood ratio test).
Branch support was computed using an aLRT (approximate likelihood ratio test) based on a chi-square distribution.
Posterior branch support was computed using both approximate Likelihood Ratio test (aLRT) (Anisimova and Gascuel 2006) and bootstrap analysis (with 100 replicates).
To quantify dendrite arborization, we manually traced the outline of the cell and dendritic branches of 10 randomly selected Purkinje cells from each experiment, and the area was computed using NIH Image software (Vischer 2006).
A maximum likelihood tree was computed using phyml-alrt (JTT matrix, six rate categories, gamma parameter 1.0), which also computes aLRT branch support in computing time compatible with very large trees [ 35].
95% CI was computed using t-distribution.
bExpected heterozygosity was computed using Nei (1987).
Differential expression was computed using limma [ 30].
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