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Human postmortem brains were obtained from the University of Pennsylvania, CNDR Brain Bank66.
Mouse brains were obtained and each hypothalamus was separated and snap frozen in liquid nitrogen.
Forty-eight hours after MCAO, coronal sections of adult brains were obtained and stained with 2,3,5-triphenyl tetrazolium chloride.
Brains were obtained at autopsy from 18 right-handed Japanese patients with schizophrenia (10 men, eight women, mean age=62.4 years, SD=15.7) and nine right-handed control subjects (seven men, two women, mean age=58.6 years, SD=13.8) who were without any history of neuropsychiatric disorders (Table 1).
Both in vivo and ex vivo images of the rat brains were obtained using the Inveon microPET scanner and were analyzed using the Acquisition Sinogram Image Processing (ASIPRO, Siemens Medical Solutions USA, Inc., Knoxville, TN, USA) and Pixelwise Modeling Software (PMOD Technologies, Zurich, Switzerland).
Human brains were obtained 12 24 hrs postmortem.
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Spatial gene expression data from six adult human brains was obtained from the Allen Human Brain Atlas database (AHBA)59.
Total RNA from post-mortem human brains was obtained from Ambion (Austin, USA) and Capital Biosciences (Rockville, USA).
TSS/promoter and enhancer regions for mouse E14.5 brain were obtained from enhancer promoter units identified by the ENCODE project.
A set of in vivo 1H and 23Na axial images to cover the whole rat brain were obtained.
The radioactivity counts for PET in the frontal cortex, somatosensory cortex, visual cortex, striatum, thalamus, pons, cerebellum, hippocampus, midbrain, and whole brain were obtained.
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